Human Malformations and Related Anomalies
By Roger E. Stevenson, Judith G. Hall
Publisher: Oxford University Press
Number Of Pages: 1509
Publication Date: 2006
ISBN-10 / ASIN: 0195165683
ISBN-13 / EAN: 9780195165685
From the Preface:
Over a decade has separated the first and second editions of Human Malformations and Related Anomalies. This interval has been eventful from many standpoints. A major birth defects prevention strategy - periconceptional folic acid utilization - has proved effective in large-scale studies in several countries. New understandings of the genetic basis for malformations and malformation syndromes have emerged and made possible prenatal and postnatal laboratory diagnostic technologies. While molecular advances may be considered the most spectacular, significant advances in the biochemical and cytogenetic bases for malformations have also been impressive. The interval has brought us to the threshold of recognition of potential roles that epigenetic mechanisms, genomic changes, and disruption of molecular pathways exert on human development.
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