Ions in the Brain: Normal Function, Seizures, and Stroke
Ions in the Brain: Normal Function, Seizures, and Stroke
By George G. Somjen
Publisher: Oxford University Press, USA
Number Of Pages: 504
Publication Date: 2004-01-29
ISBN-10 / ASIN: 0195151712
ISBN-13 / EAN: 9780195151718
Binding: Hardcover
Ions, their transport across membranes, and their flow through specialized ion channels are central to the understanding of brain function, normal and pathological. The first part of this book deals http://www.book4doc.com/60017 the regulation of ions in brain extra- and intracellular fluids. Regulation is effected
by the blood-brain barrier, and by membrane ion pumps and other transport mechanisms of neurons and glial cells. Normally adjusted http://www.book4doc.com/60017 optimal neural function, ion levels can change and alter the excitability of neurons and influence synaptic transmission in healthy and diseased brains. After an
introduction to the electrophysiology of epilepsy, and a description of experimental seizure "models," the second part discusses the roles of the faulty regulation of ions and of the diseases of ion channels in generating epileptic seizures. The mechanisms of action of various anticonvulsant drugs
are also considered. The third part is devoted to the phenomenon of spreading depression and its likely role in human diseases. The final chapters of the book deal with the role of ions in the devastation caused by lack of oxygen and by insufficient blood flow to brain tissue, and the reasons for
the exceptional vulnerability of certain classes of central neurons in hypoxia and stroke. The book will be of interest to neuroscientists, neurobiologists, neurophysiologists, neurologists, neurosurgeons, and to their students and trainees.
Summary: An extensive scientific monography written with style
Rating: 5
I've been doing some shamefully overdue reading lately and the reason of this review is to let others know about the delight I experienced in reading George Somjen's book on ions. I have no reserve in saying that the author is, at least for me, the most accomplished writer of the neuroscientific community. And this is why: stylishly speaking I read this book as if it was a thriller, I couldn't let it out of the hand before the end, and then I was sorry that it was over. Secondly, I rarely witnessed so much fairplay with respect to others' work and so much modesty towards its own. This comes accompanied by an encyclopedic culture of the literature that makes Somjen's writings true handbooks and even more so for poorly cultivated young scientists who think that neuroscience started when they opened their eyes. I like very much the balance between concepts known to create controversy nowadays, but this is far from emerging from Somjen's writing. And finally this book made me happy because I had the feeling of learning without effort.
size: 26835K pass: giga
http://www.book4doc.com/49570
Ions in the Brain: Normal Function, Seizures, and Stroke
By George G. Somjen
Publisher: Oxford University Press, USA
Number Of Pages: 504
Publication Date: 2004-01-29
ISBN-10 / ASIN: 0195151712
ISBN-13 / EAN: 9780195151718
Binding: Hardcover
Ions, their transport across membranes, and their flow through specialized ion channels are central to the understanding of brain function, normal and pathological. The first part of this book deals http://www.book4doc.com/60017 the regulation of ions in brain extra- and intracellular fluids. Regulation is effected
by the blood-brain barrier, and by membrane ion pumps and other transport mechanisms of neurons and glial cells. Normally adjusted http://www.book4doc.com/60017 optimal neural function, ion levels can change and alter the excitability of neurons and influence synaptic transmission in healthy and diseased brains. After an
introduction to the electrophysiology of epilepsy, and a description of experimental seizure "models," the second part discusses the roles of the faulty regulation of ions and of the diseases of ion channels in generating epileptic seizures. The mechanisms of action of various anticonvulsant drugs
are also considered. The third part is devoted to the phenomenon of spreading depression and its likely role in human diseases. The final chapters of the book deal with the role of ions in the devastation caused by lack of oxygen and by insufficient blood flow to brain tissue, and the reasons for
the exceptional vulnerability of certain classes of central neurons in hypoxia and stroke. The book will be of interest to neuroscientists, neurobiologists, neurophysiologists, neurologists, neurosurgeons, and to their students and trainees.
Summary: An extensive scientific monography written with style
Rating: 5
I've been doing some shamefully overdue reading lately and the reason of this review is to let others know about the delight I experienced in reading George Somjen's book on ions. I have no reserve in saying that the author is, at least for me, the most accomplished writer of the neuroscientific community. And this is why: stylishly speaking I read this book as if it was a thriller, I couldn't let it out of the hand before the end, and then I was sorry that it was over. Secondly, I rarely witnessed so much fairplay with respect to others' work and so much modesty towards its own. This comes accompanied by an encyclopedic culture of the literature that makes Somjen's writings true handbooks and even more so for poorly cultivated young scientists who think that neuroscience started when they opened their eyes. I like very much the balance between concepts known to create controversy nowadays, but this is far from emerging from Somjen's writing. And finally this book made me happy because I had the feeling of learning without effort.
size: 26835K pass: giga
http://www.book4doc.com/49570
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